Wat voor bijwerkingen heeft atorvastatine?
Wat zijn de mogelijke bijwerkingen van Atorvastatine? Atorvastatine kan bijwerkingen veroorzaken. Neem contact op met uw arts als u hevige spierpijn, gewrichtspijn, spierzwakte, spierkramp of een spierscheuring krijgt. U kunt last krijgen van buikpijn, verstopping, winderigheid, misselijkheid, zuurbranden of diarree.
Is atorvastatin soluble or insoluble in water?
Freely soluble in methanol; slightly soluble in ethanol; very slightly soluble in acetonitrile, distilled water, phosphate buffer (pH 7.4). Insoluble in aqueous solutions of pH 4 and below. / Atorvastatin calcium salt trihydrate / O’Neil, M.J. (ed.). The Merck Index – An Encyclopedia of Chemicals, Drugs, and Biologicals.
What are the pros and cons of atorvastatin?
2.Upsides 1 Atorvastatin, in conjunction with dietary measures, may be used for the treatment of high cholesterol in people at… 2 Atorvastatin is also used to lower the risk of coronary events (such as a heart attack, stroke, or angina) in patients… 3 Possibly more effective than other statins. 4 Generic atorvastatin is available. More
What is atorvastatin calcium?
(atorvastatin calcium) is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin calcium is [R-(R*, R*)]-2-(4-fluorophenyl)-ß, -dihydroxy-5
How is atorvastatin eliminated from the body?
Atorvastatin and its metabolites are mainly eliminated in the bile without enterohepatic recirculation. The renal elimination of atorvastatin is very minimal and represents less than 1% of the eliminated dose. The reported volume of distribution of atorvastatin is of 380 L. The registered total plasma clearance of atorvastatin is of 625 ml/min.