Inhoudsopgave
Wat is ARVD?
Aritmogene cardiomyopathie (ACM), ook wel ARVC (aritmogene rechter ventrikel cardiomyopathie) of ARVD (aritmogenic right ventricle dysplasia) genoemd, is een ziekte van de hartspier, waarbij gedeelten van de hartspier zijn vervangen door vet- of bindweefsel en waarbij er vaker ernstige ritmestoornissen voorkomen.
Wat is een hartspierziekte?
Cardiomyopathie is een aandoening van de hartspier. Het hart kan minder goed samentrekken of ontspannen. Dan pompt het bloed minder goed rond.
What is the goal of genetic testing for ARVD?
The goal of genetic testing is to identify the genetic change causing ARVD — Arrhythmogenic Right Ventricular Dysplasia (also known as Arrhythmogenic Right Ventricular Cardiomyopathy — ARVC) — in a family and then find out who else in the family inherited that genetic change.
What is the genetic basis of ARVD/C?
The genetic basis of ARVD/C is complex and not fully understood. There are several different patterns of inheritance observed in ARVD/C: In autosomal dominant inheritance, a person with a gene change predisposing them to ARVD/C has a 50% chance of passing on that same predisposition to their child.
Is there a family history of ARVD?
A family history of ARVD is present in at least 30 to 50 percent of cases. Therefore, it is recommended that all first- and second-degree family members (parents, siblings, children, grandchildren, uncle, aunt, nephew, niece) be evaluated carefully for this form of cardiomyopathy, even in the absence of symptoms.
What is arrhythmogenic right ventricular dysplasia (ARVD)?
Arrhythmogenic right ventricular dysplasia (ARVD), also known as arrhythmogenic right ventricular cardiomyopathy (ARVC), is a leading cause of sudden death among young athletes but it can affect people of all ages and all activity levels. Learn more about the symptoms and diagnosis for ARVD/C.