What is a meningioma?

What is a meningioma?

Meningiomas are almost always benign tumors arising in the meninges (covering the brain) they can enlarge over time and may calcify. 4.9k views Reviewed >2 years ago

What are the treatment options for meningiomas of the brain?

Meningiomas usually can be surgically resected (removed) and result in a permanent cure if the tumor is superficial on the dural surface and easily accessible. Transarterial embolization has become a standard preoperative procedure in the preoperative management. If invasion of the adjacent bone occurs, total removal is nearly impossible.

What can microarray-based gene expression profiling tell us about meningioma progression?

“Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression”. International Journal of Cancer. 114 (2): 249–256. doi: 10.1002/ijc.20733.

What is the prevalence of meningiomata?

About one per thousand people in the United States are currently affected. Onset is usually in adults. In this group they represent about 30% of brain tumors. Women are affected about twice as often as men. Meningiomata were reported as early as 1614 by Felix Plater.

Overview A meningioma is a tumor that arises from the meninges — the membranes that surround your brain and spinal cord. Although not technically a brain tumor, it is included in this category because it may compress or squeeze the adjacent brain, nerves and vessels. Meningioma is the most common type of tumor that forms in the head.

What is the pathophysiology of meningioma of the temporal bone?

Meningiomas involving the temporal bone may originate from arachnoid cell nests present within the temporal bone (intratemporal), but more frequently originate from arachnoid cell nests of the posterior or middle cranial fossa with secondary invasion of the TB (extratemporal).

What are the surgical options for temporal bone meningiomas?

Surgical treatment of temporal bone meningiomas is associated with high recurrence rate due to indiscreet tumor margins. Combined surgical approaches (temporal craniotomy and mastoidectomy) by neurosurgical and otological teams are recommended for meningiomas originating in the temporal bone.

What is a dura mater meningioma?

The dura mater is one of three layers that form the meninges. Meningiomas arise from meningeal cells. As a result, they tend to occur along the surface of the brain. Do atypical and anaplastic meningiomas spread?

This means it begins in the brain or spinal cord. Overall, meningiomas are the most common type of primary brain tumor. However, higher grade meningiomas are very rare. To get an accurate diagnosis, a piece of tumor tissue will be removed during surgery, if possible.

What percentage of meningiomas are intradural extramedullary?

The vast majority (90%) of spinal meningiomas are intradural extramedullary in location. Occasionally (5%), purely extradural tumors are found. The remainder (5%) have both intradural and extradural components taking on a dumbbell appearance 2 .

What is the treatment for spinal meningioma?

Spinal meningiomas are typically slow growing. Surgery is the treatment of choice and complete tumor removal is achieved in the vast majority of patients. Less than 10% experience recurrence 2.