Inhoudsopgave
Wat zijn de effecten van GLP-1 analogen?
Als reactie op eten stimuleren deze hormonen afkomstig uit de dunne darm de alvleesklier tot afgifte van insuline. Het incretine hormoon GLP-1 (glucagon-like peptide 1) remt ook de afgifte van glucagon, vertraagt het ledigen van de maag en vermindert de eetlust.
Welk middel hoogste daling HbA1c?
Resultaten
| Metformine + SU-derivaat | Metformine + SGLT-2-remmer | |
|---|---|---|
| HbA1c-verlaging na 6 maanden (mmol/mol) | 14,5 | 13,8 |
| HbA1c-verlaging na 12 maanden (mmol/mol) | 14,2 | 14,4 |
| HbA1c-verlaging na 18 maanden (mmol/mol) | 13,2 | 16,0 |
Wat zijn GLP-1 analogen?
GLP-1-receptoragonisten (ook wel incretinemimetica of GLP-1-analogen genoemd) zijn bloedglucoseverlagende middelen die ingrijpen op het incretinesysteem. GLP-1-receptoragonisten binden zich aan de GLP-1-receptor en activeren deze.
What are GLP-1 receptor agonists?
GLP-1 receptor agonists are a type of non-insulin medication that is used in combination with diet and exercise to help treat type 2 diabetes.
What are the warnings and precautions for GLP-1 receptor agonists?
Other warnings and precautions include pancreatitis and thyroid cell carcinomas. GLP-1 receptor agonists are an innovative and effective option to improve blood glucose control, with other potential benefits of preserving beta-cell function, weight loss, and increasing insulin sensitivity.
What are glucagon-like peptide-1 receptor agonists for type 2 diabetes?
Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are attractive options for the treatment of type 2 diabetes (T2D) because they effectively lower A1C and weight while having a low risk of hypoglycemia. The GLP-1 RA class has grown in the last decade with several agents available for use in the US and Europe and several more in development.
Do glucagon-like peptide-1 receptors (GLP-1 Ras) affect weight?
Changes in weight with GLP-1 RAs in head-to-head clinical studies. *p< 0.05 GLP-1 RA, glucagon-like peptide-1 receptor agonists.