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What is a granuloma?
A granuloma is a little lump, or nodule. It is a clump of immune cells or white blood cells. Granulomas can be part of the immune system’s response to: When the cells clump together, they protect the body from potential threats in two ways.
What is chronic granulomatous disease?
Chronic granulomatous (gran-u-LOM-uh-tus) disease (CGD) is an inherited disorder that occurs when a type of white blood cell (phagocyte) that usually helps your body fight infections doesn’t work properly. As a result, the phagocytes can’t protect your body from bacterial and fungal infections.
Are all granulomas calcified?
Not all granulomas are calcified. Granulomas are made up of a spherical cluster of cells that surrounds the inflamed tissue. They can eventually calcify over time. A calcified granuloma has a similar density to bone and will appear more brightly than the surrounding tissue on an X-ray.
What are the possible complications of granulomas?
The process of granuloma formation can sometimes be disruptive to tissue function. For example, the parasitic infection schistosomiasis can cause granulomas to form around the parasite’s eggs in the liver. The process of granuloma formation can in turn lead to fibrosis of the liver.
A granuloma is a small area of inflammation. Granulomas are often found incidentally on an X-ray or other imaging test done for a different reason. Typically, granulomas are noncancerous (benign). Granulomas frequently occur in the lungs, but can occur in other parts of the body and head as well.
Can a granuloma recur after surgery?
However, granulomas often quickly recur despite excision – thus surgery is reserved only in cases where a granuloma is large enough to cause shortness of breath.
What is a suture granuloma?
A suture granuloma forms as a result of the body’s immune system attempting to wall off the foreign substance from surrounding body tissues.
What is granuloma annulare and how is it treated?
Granuloma annulare is a skin condition that causes a raised rash or bumps (lesions) in a ring pattern, usually on the hands and feet. Granuloma annulare (gran-u-LOW-muh an-u-LAR-e) is a skin condition that causes a raised rash or bumps (lesions) in a ring pattern. The most common type affects young adults and usually affects the hands and feet.
Can granuloma annulare go away on its own?
Your doctor may diagnose granuloma annulare by examining the affected skin and taking a small skin sample (biopsy) to examine under a microscope. Granuloma annulare can clear on its own over time. Treatment might help clear the skin faster than if left untreated, but recurrence is common.
What is the pathophysiology of nodular granuloma annulare?
Necrotizing granulomas can develop in patients with rheumatoid arthritis, typically manifesting as bumps in the soft tissues around the joints (so-called rheumatoid nodules) or in the lungs. Granuloma annulare is a skin disease of unknown cause in which granulomas are found in the dermis of the skin, but it is not a true granuloma.
What are the treatment options for granulomas?
Because granulomas are usually the result of a diagnosable condition, treatment of the underlying condition is important. For example, a bacterial infection in your lungs that triggers granuloma growth should be treated with antibiotics.